Pins and needles, tingling and numbness in the tips of fingers and toes can also develop from low folic acid or folate deficiency following ongoing high Vitamin B12 supplementation or injections, which is why folate status should always be checked whenever Vitamin B12 is taken for longer periods of time. The same applies when folic acid is regularly supplemented, which can likewise lead to Vitamin B12 deficiency and the typical tingling and numbness symptoms, with the potential of causing permanent nerve damage... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...